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Claire Linturn Group

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Hector Tarasov
Hector Tarasov

Mini International Neuropsychiatric Interview 7.0 Pdf 38

The Mini-International Neuropsychiatric Interview (M.I.N.I.) is a short structured diagnostic interview, developed jointly by psychiatrists and clinicians in the United States and Europe, for DSM-IV and ICD-10 psychiatric disorders. With an administration time of approximately 15 minutes, it was designed to meet the need for a short but accurate structured psychiatric interview for multicenter clinical trials and epidemiology studies and to be used as a first step in outcome tracking in nonresearch clinical settings. The authors describe the development of the M.I.N.I. and its family of interviews: the M.I.N.I.-Screen, the M.I.N.I.-Plus, and the M.I.N.I.-Kid. They report on validation of the M.I.N.I. in relation to the Structured Clinical Interview for DSM-III-R, Patient Version, the Composite International Diagnostic Interview, and expert professional opinion, and they comment on potential applications for this interview.

mini international neuropsychiatric interview 7.0 pdf 38

The M.I.N.I. was developed by Sheehan et al. [14] to explore some psychiatric disorders according to the DSM and ICD diagnostic criteria. Every few years, the M.I.N.I. is updated and validated versions in other languages also become available [14]. Initially, the M.I.N.I. was designed to meet the need for a short yet valid and reliable psychiatric interview for multicenter clinical trials and epidemiological studies. However, in recent years, the assessment tool is also being used in humanitarian aid and global health settings [7]. The M.I.N.I. is particularly attractive since it offers a fee waiver for researchers and clinicians who will use the assessment to assist refugees or victims of terrorism (for more information see -international-neuropsychiatric-interview-mini/). This stipulation may be more relevant now than ever, as refugee groups resettle worldwide.

A sample of 102 participants was recruited between April 2019 to March 2020. Inclusion criteria were defined as age between 18 and 75 years and native Arabic speakers. Initially, two interviewers received in-depth structured training and supervision by two licensed psychologists to ensure consistency in the administration of the interview process. In the next step, participants received an information sheet about the study aims and were asked for their interest in participation. Throughout the whole study process, participants were encouraged to ask any questions that remain unclear. Participants who were interested and willing to participate gave their signed informed consent before any trial-related procedures were conducted. Study participation was voluntary, and no monetary compensation was provided. In the next step, participant symptomatology was assessed by using rater-based and self-rated measures, including the Mini International Neuropsychiatric Interview (M.I.N.I.), the Patient Health Questionnaire (PHQ-9), and the Harvard Trauma Questionnaire (HTQ). All assessments were conducted in Arabic. In parallel, participants were also seen by an Arabic-speaking licensed psychiatrist for a diagnostic assessment and consultation. Three separate psychiatrists were available in rotation at the outpatient clinic. Both interviewers and the psychiatrist were blind to the diagnosis of each other. The whole assessment procedure took between 60 and 90 min. The study was approved by the ethics committee of Charité - Universitätsmedizin Berlin, Germany, and is in line with the Declaration of Helsinki.

Recent studies have highlighted that patients from a Muslim cultural background may experience feelings of discomfort when alone with a therapist from the opposite gender [38], sometimes resulting in an inaccurate representation of symptoms during psychiatric evaluation. In the present study, gender may have played a role in participant responses. Matching gender between psychiatrists and patients was not always possible in the expert interviews, whereas there was more flexibility in the administration of the M.I.N.I.. Since the M.I.N.I. was designed to be administered by non-specialists, it provides an efficient solution to the shortage of available specialized professional care, who sometimes lack the language skills and cultural competence training needed in diagnosing Arabic-speaking populations. Taken together, these reports may explain the slight to moderate Kappa values when comparing the M.I.N.I.-AR and expert diagnoses. Nonetheless, the specific effect of matching gender was not within the scope of this paper, however, it may be interesting to assess this in future validation studies.

Another factor that may be important in accounting for cases of depression among patients with COPD is the method used to identify depression. Despite numerous reports of a higher prevalence of depression in patients with COPD, it is important to recognize that most studies analyze the symptoms of depression without emphasizing the diagnosis [5, 8]. Therefore, this study aimed to analyze the influence of depression using a diagnostic tool, the mini international neuropsychiatric interview plus (MINI), rather than an analysis of the symptoms, to determine the effect of depression on functional capacity and quality of life among patients with COPD.

Some details of the present study that may help in understanding the results are described as follows. This study used a structured interview for the diagnosis of depression, performed by only one trained psychiatrist, who was blinded to the evaluation results from the functional tests performed by the physiotherapist or the pulmonary function results performed by the pulmonologist. In addition to the structured interview, this study also administered a quality of life questionnaire specific to COPD. Moreover, a broad-scoped assessment of functional capacity was performed by a physical therapist who had no knowledge regarding the results of the psychiatric evaluation. This study used a population from a clinical setting in a cross-sectional study. Some limitations exist in this study. Because this was a cross-sectional study, it was not possible to establish causal relationships to support the existence of a temporal sequence between the exposure factor and the subsequent development of the disease. Additionally, this work was carried out with a sample of convenience, which may limit the ability of our results to be generalized.

The MINI29 is a short, semi-structured, diagnostic interview designed to be administered by trained lay interviewers. It has good concordance with the Structured Clinical Interview for DSM30 (SCID) and the Composite International Diagnostic Interview.31 The MINI is compatible with both the International Classifications of Diseases-10 and the DSM-IV. There is good concordance between the PTSD module of the MINI and the PTSD section of the SCID. 29,32

Another limitation is that we did not use a validated gold standard DSM-5 PTSD interview as the diagnostic criterion. Although the DSM-IV PTSD module of the MINI has been used in other validation studies41 and our modifications to the MINI were consistent with the DSM-5 PTSD diagnosis, future studies will need to use a validated clinician administered diagnostic measure like the CAPS-5.42 However, our results are an important first step that allows for the implementation of the PC-PTSD-5 in primary care clinics and which, we hope, will encourage additional research exploring whether the cutoffs reported here are appropriate for all settings and populations. Finally, the results of our pilot26 and current study do not take comorbidity or other spectrum effects (i.e., variation among the groups with and without PTSD) into consideration.43 It is possible that individuals with certain characteristics (e.g., demographic features or comorbid psychopathology) require different cutoff scores. Future research is needed to examine this possibility.

A multi-stage random sampling was used to find households for inclusion in the survey. The selection of villages (the smallest administrative unit in Rwanda), households and study participants in the eight districts of the Southern province of Rwanda was made in three phases. Out of the total number of 3512 existing villages, 35 villages were randomly selected using a random function. The number of households in each village was selected proportionate to the total number of households in each village and the person to be interviewed was randomly selected among eligible people in each household i.e. men and women aged between 20 and 35 years. The first participant in each village was selected from the closest household to the center of the village and a calculated sampling interval was applied to get the next household.

To assess the mental health status, four modules from the MINI International Neuropsychiatric interview (DSM-IV) version 5.0.0, were used to identify major depressive episodes in the past two weeks and in earlier periods of 2 week-duration or more, generalized anxiety disorder, suicide risk and post-traumatic stress disorder (PTSD). The MINI is designed as a brief structured interview for diagnosing the major psychiatric disorders according to DSM-IV criteria and International Classification of Diseases-10. Validation studies show that the MINI has similar validity and reliability properties as the WHO-CIDI (Composite International Diagnostic Interview for ICD-10) instrument [22]. The advantage with the MINI is that it contains less items, takes less time to administer and can be used by trained interviewers but does not necessarily require clinical staff. To measure physical, sexual and psychological violence exposure, we used the items from the Women's Health and Life experiences questionnaire, developed by WHO [23] and used in several countries all over the world [24]. The questionnaires were translated in Kinyarwanda, one of the national languages in Rwanda.

We are conducting a randomized, double-blind, placebo-controlled trial of oxytocin-enhanced motivational interviewing group therapy (MIGT). Oxytocin or placebo 40 IU is administered intranasally in conjunction with six, weekly MIGT sessions. We will recruit 50 MSM, initiating treatment for MUD from specialized community health programs in San Francisco, CA, USA. Individuals will be randomized (1:1) to receive six, weekly sessions of MIGT with or without oxytocin. Our primary outcome is session attendance. Other outcomes of interest include: measures of group cohesion, anxiety, psychophysiology, and stimulant craving and use.


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